Brief Information of the Compound and Protein
Compound Name
 Compound Info 
ethyl 4-[(2R)-3-(3-carbamimidoylphenyl)-2-[[2,4,6-tri(propan-2-yl)phenyl]sulfonylamino]propanoyl]piperazine-1-carboxylate
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 PubChem ID
CID: 92220134
Canonical SMILES
CCOC(=O)N1CCN(CC1)C(=O)[C@@H](Cc1cccc(c1)C(N)=N)NS(=O)(=O)c1c(cc(cc1C(C)C)C(C)C)C(C)C
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Compound Formula C32H47N5O5S
Compound Structure
Protein Name
 Protein Info 
Serine protease hepsin
Protein Classification
Enzyme
>
Protease
>
Serine protease
Uniprot ID
P05981
Gene Name
HPN
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000243 MCF-10A
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 6490 nM
   TI
   LI
   LO
   TS
CL000265 NS0
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 3350 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3000 nM