Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CHEMBL3715469
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Canonical SMILES
COc1cc(cnc1N)-c1cc([C@@H]2[C@H]3CN(C[C@@H]23)C2COC2)n(n1)C(C)C
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Compound Formula C20H27N5O2
Compound Structure
Protein Name
 Protein Info 
Mitogen-activated protein kinase kinase kinase 12
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
Uniprot ID
Q12852
Gene Name
MAP3K12
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 873 nM
   TI
   LI
   LO
   TS
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Ki = 7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 7.4 nM