Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-chloro-5-[5-[1-(oxetan-3-yl)piperidin-4-yl]-1-propan-2-ylpyrazol-3-yl]-1H-pyrrolo[2,3-b]pyridine
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 PubChem ID
CID: 90286662
Canonical SMILES
CC(C)n1nc(cc1C1CCN(CC1)C1COC1)-c1cnc2[nH]cc(Cl)c2c1
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Compound Formula C21H26ClN5O
Compound Structure
Protein Name
 Protein Info 
Mitogen-activated protein kinase kinase kinase 12
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
Uniprot ID
Q12852
Gene Name
MAP3K12
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 574 nM
   TI
   LI
   LO
   TS
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Ki = 15 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 15 nM