Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[5-[(1S,5R)-3-(oxetan-3-ylmethyl)-3-azabicyclo[3.1.0]hexan-6-yl]-1-propan-2-ylpyrazol-3-yl]-3-(trifluoromethyl)pyridin-2-amine
    Show/Hide
Canonical SMILES
CC(C)n1nc(cc1[C@@H]1[C@H]2CN(CC3COC3)C[C@@H]12)-c1cnc(N)c(c1)C(F)(F)F
    Show/Hide
Compound Formula C21H26F3N5O
Compound Structure
Protein Name
 Protein Info 
Mitogen-activated protein kinase kinase kinase 12
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
Uniprot ID
Q12852
Gene Name
MAP3K12
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 274 nM
   TI
   LI
   LO
   TS
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Ki = 5 nM
   TI
   LI
   LO
   TS