Brief Information of the Compound and Protein
Compound Name
 Compound Info 
8-[(2R)-2-hydroxy-2-(4-methyl-1-oxo-3H-2-benzofuran-5-yl)ethyl]-2-(3-methoxy-1,2,4-thiadiazol-5-yl)-2,8-diazaspiro[4.5]decan-1-one
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 PubChem ID
CID: 130449692
Canonical SMILES
COc1nsc(n1)N1CCC2(CCN(C[C@H](O)c3ccc4C(=O)OCc4c3C)CC2)C1=O
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Compound Formula C22H26N4O5S
Compound Structure
Protein Name
 Protein Info 
ATP-sensitive inward rectifier potassium channel 1
Protein Classification
Ion channel
>
Voltage-gated ion channel
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Potassium channels
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Inwardly rectifying potassium channel
Uniprot ID
P48048
Gene Name
KCNJ1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 17 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 23 nM
   TI
   LI
   LO
   TS