Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(6E)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
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 PubChem ID
CID: 1548943
SID: 14923155
Canonical SMILES
COc1cc(CNC(=O)CCCC\C=C\C(C)C)ccc1O
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Compound Formula C18H27NO3
Compound Structure
Protein Name
 Protein Info 
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
>
Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
Q8NER1
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
EC50 = 44.8 nM
   TI
   LI
   LO
   TS
2
Ki = 1140 nM
   TI
   LI
   LO
   TS
3
Ki = 2530 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  8
1
EC50 = 2.512 nM
   TI
   LI
   LO
   TS
2
EC50 = 3.9 nM
   TI
   LI
   LO
   TS
3
EC50 = 5.3 nM
   TI
   LI
   LO
   TS
4
EC50 = 19.95 nM
   TI
   LI
   LO
   TS
5
EC50 = 20 nM
   TI
   LI
   LO
   TS
6
EC50 = 29 nM
   TI
   LI
   LO
   TS
7
EC50 = 40 nM
   TI
   LI
   LO
   TS
8
IC50 = 8 nM
   TI
   LI
   LO
   TS
CL000004 SH-SY5Y
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 6 nM