Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[1-[6-(2,4-difluorophenoxy)pyrimidin-4-yl]piperidin-4-yl]-(1,3-dihydroisoindol-2-yl)methanone
    Show/Hide
 PubChem ID
CID: 137654353
Canonical SMILES
Fc1ccc(Oc2cc(ncn2)N2CCC(CC2)C(=O)N2Cc3ccccc3C2)c(F)c1
    Show/Hide
Compound Formula C24H22F2N4O2
Compound Structure
Protein Name
 Protein Info 
Muscarinic acetylcholine receptor M5
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Acetylcholine receptor
Uniprot ID
P08912
Gene Name
CHRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1130 nM
   TI
   LI
   LO
   TS