Brief Information of the Compound and Protein
Compound Name
N-(3-cyanopyrazolo[1,5-a]pyridin-5-yl)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butanamide
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PubChem ID
CID: 137644966
Canonical SMILES
Clc1cccc(N2CCN(CCCC(=O)Nc3ccn4ncc(C#N)c4c3)CC2)c1Cl
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Compound Formula C22H22Cl2N6O
Compound Structure
Protein Name
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 2.3 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T Homo sapiens (Human)  1
1
EC50 = 62 nM
   TI
   LI
   LO
   TS