Brief Information of the Compound and Protein
Compound Name
N-(1-adamantyl)-4-[4-[1-[(3,4-dimethoxyphenyl)methyl]-6-oxopyridin-3-yl]-6-(trifluoromethyl)pyrimidin-2-yl]sulfonylbutanamide
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PubChem ID
CID: 134202169
Canonical SMILES
COc1ccc(Cn2cc(ccc2=O)-c2cc(nc(n2)S(=O)(=O)CCCC(=O)NC23CC4CC(CC(C4)C2)C3)C(F)(F)F)cc1OC
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Compound Formula C33H37F3N4O6S
Compound Structure
Protein Name
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P21912
Gene Name
SDHB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  2
1
EC50 = 0.23 nM
   TI
   LI
   LO
   TS
2
EC50 = 0.42 nM
   TI
   LI
   LO
   TS