Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9428456, 1.293
    Show/Hide
 PubChem ID
CID: 129625998
Canonical SMILES
Clc1ccc(cc1)C(=O)Nc1nc(CN2CCC(CC2)C(=O)NC2CCCC2)cs1
    Show/Hide
Compound Formula C22H27ClN4O2S
Compound Structure
Protein Name
 Protein Info 
Atypical chemokine receptor 3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CXC chemokine receptor
Uniprot ID
P25106
Gene Name
ACKR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000857 PathHunter CHO-K1 CXCR7 beta-arrestin
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 81 nM
   TI
   LI
   LO
   TS