Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9428456, 2.028
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 PubChem ID
CID: 129626147
Canonical SMILES
COc1cccc(CNC(=O)C2CCN(Cc3cccc(NC(=O)c4ccc(Cl)cc4)c3)CC2)c1
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Compound Formula C28H30ClN3O3
Compound Structure
Protein Name
 Protein Info 
Atypical chemokine receptor 3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CXC chemokine receptor
Uniprot ID
P25106
Gene Name
ACKR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000857 PathHunter CHO-K1 CXCR7 beta-arrestin
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 394 nM
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   LI
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