Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9428456, 1.262
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 PubChem ID
CID: 129625981
Canonical SMILES
Cc1nc(C)c(CC(=O)Nc2cccc(CN3CCC(CC3)C(=O)NC(C)(C)C)c2)s1
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Compound Formula C24H34N4O2S
Compound Structure
Protein Name
 Protein Info 
Atypical chemokine receptor 3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Chemokine receptor
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CXC chemokine receptor
Uniprot ID
P25106
Gene Name
ACKR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000857 PathHunter CHO-K1 CXCR7 beta-arrestin
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 120 nM
   TI
   LI
   LO
   TS