Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9428456, 1.238
    Show/Hide
 PubChem ID
CID: 129626193
Canonical SMILES
CC(C)(C)NC(=O)C1CCN(Cc2cccc(NC(=O)c3ccc(cc3)C(F)(F)F)c2)CC1
    Show/Hide
Compound Formula C25H30F3N3O2
Compound Structure
Protein Name
 Protein Info 
Atypical chemokine receptor 3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CXC chemokine receptor
Uniprot ID
P25106
Gene Name
ACKR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000857 PathHunter CHO-K1 CXCR7 beta-arrestin
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 4 nM
   TI
   LI
   LO
   TS