Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-methyl 1-(4-(1-isopropyl-3-(3-(methylsulfonamido)phenyl)-1H-pyrazol-4-yl)pyrimidin-2-ylamino)propan-2-ylcarbamate
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 PubChem ID
CID: 51033802
SID: 117693975
Canonical SMILES
COC(=O)N[C@@H](C)CNc1nccc(-c2cn(C(C)C)nc2-c2cccc(NS(C)(=O)=O)c2)n1
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Compound Formula C22H29N7O4S
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
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TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000045 A-375
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1150 nM
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