Brief Information of the Compound and Protein
Compound Name
N-(5-chloro-3-(4-(2-(2-cyanoethylamino)pyrimidin-4-yl)-1-isopropyl-1H-pyrazol-3-yl)-2-fluorophenyl)methanesulfonamide
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PubChem ID
CID: 51034122
SID: 117694292
Canonical SMILES
CC(C)n1cc(-c2ccnc(NCCC#N)n2)c(-c2cc(Cl)cc(NS(C)(=O)=O)c2F)n1
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Compound Formula C20H21ClFN7O2S
Compound Structure
Protein Name
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TKL protein kinase group
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TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000045 A-375 Homo sapiens (Human)  1
1
IC50 = 2 nM
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