Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US10568884, Cpd 16
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 PubChem ID
CID: 51033684
SID: 117693860
Canonical SMILES
COC(=O)N[C@@H](C)CNc1nccc(n1)-c1cn(nc1-c1ccnc(NS(C)(=O)=O)c1F)C(C)C
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Compound Formula C21H27FN8O4S
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000045 A-375
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 24 nM