Brief Information of the Compound and Protein
Compound Name
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)-N-(2-hydroxyethyl)acetamide
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PubChem ID
CID: 68208886
Canonical SMILES
COc1cc(OC)cc(N(CC(=O)NCCO)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1
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Compound Formula C24H26N6O4
Compound Structure
Protein Name
Fibroblast growth factor receptor 3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22607
Gene Name
FGFR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  3
1
IC50 = 158.49 nM
   TI
   LI
   LO
   TS
2
IC50 = 891.25 nM
   TI
   LI
   LO
   TS
3
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 12.88 nM
   TI
   LI
   LO
   TS