Brief Information of the Compound and Protein
Compound Name
N-(3,5-dimethoxyphenyl)-N-(2-((3R,5R)-3,5-dimethylpiperidin-1-yl)ethyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine hydrochloride
    Show/Hide
PubChem ID
CID: 134155437
Canonical SMILES
COc1cc(OC)cc(N(CCN2C[C@H](C)C[C@@H](C)C2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1.Cl
    Show/Hide
Compound Formula C29H37ClN6O2
Compound Structure
Protein Name
Fibroblast growth factor receptor 3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22607
Gene Name
FGFR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  3
1
IC50 = 21.88 nM
   TI
   LI
   LO
   TS
2
IC50 = 338.84 nM
   TI
   LI
   LO
   TS
3
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 6.166 nM
   TI
   LI
   LO
   TS