Brief Information of the Compound and Protein
Compound Name
N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-(1-(2-(methylamino)ethyl)-1H-pyrazol-4-yl)quinoxalin-6-amine
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PubChem ID
CID: 68208673
Canonical SMILES
CNCCn1cc(-c2cnc3ccc(N(CC4CC4)c4cc(OC)cc(OC)c4)cc3n2)cn1
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Compound Formula C26H30N6O2
Compound Structure
Protein Name
Fibroblast growth factor receptor 3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22607
Gene Name
FGFR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  3
1
IC50 = 346.74 nM
   TI
   LI
   LO
   TS
2
IC50 = 2137.96 nM
   TI
   LI
   LO
   TS
3
IC50 = 5248.07 nM
   TI
   LI
   LO
   TS
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 5.129 nM
   TI
   LI
   LO
   TS