Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(3-(3-aminopyrrolidin-1-yl)propyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
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 PubChem ID
CID: 68209028
Canonical SMILES
COc1cc(OC)cc(N(CCCN2CCC(N)C2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1
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Compound Formula C27H33N7O2
Compound Structure
Protein Name
 Protein Info 
Fibroblast growth factor receptor 3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
P22607
Gene Name
FGFR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  3
1
IC50 = 8.71 nM
   TI
   LI
   LO
   TS
2
IC50 = 74.13 nM
   TI
   LI
   LO
   TS
3
IC50 = 7762.47 nM
   TI
   LI
   LO
   TS
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 1.413 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.66 nM