Brief Information of the Compound and Protein
Compound Name
N-(1,3-thiazol-2-yl)spiro[1-azabicyclo[2.2.2]octane-3,5'-4H-1,3-oxazole]-2'-amine
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PubChem ID
CID: 58088162
Canonical SMILES
C1N=C(Nc2nccs2)OC11CN2CCC1CC2
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Compound Formula C12H16N4OS
Compound Structure
Protein Name
Neuronal acetylcholine receptor subunit alpha-7
Protein Classification
Ion channel
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Ligand-gated ion channel
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Nicotinic acetylcholine receptor
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Nicotinic acetylcholine receptor alpha subunit
Uniprot ID
Q05941
Gene Name
CHRNA7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 200 nM
   TI
   LI
   LO
   TS
2
EC50 = 1300 nM
   TI
   LI
   LO
   TS