Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine
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 PubChem ID
CID: 43815
SID: 14924270
Canonical SMILES
Fc1ccc(cc1)[C@@H]1CCNC[C@H]1COc1ccc2OCOc2c1
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Compound Formula C19H20FNO3
Compound Structure
Protein Name
 Protein Info 
Sodium-dependent serotonin transporter
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC06 neurotransmitter transporter family
Uniprot ID
P31645
Gene Name
SLC6A4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 0.56 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  4
1
IC50 = 0.2 nM
   TI
   LI
   LO
   TS
2
Ki = 0.11 nM
   TI
   LI
   LO
   TS
3
Ki = 0.38 nM
   TI
   LI
   LO
   TS
4
Ki = 0.42 nM
   TI
   LI
   LO
   TS
CL000232 JAR
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 20 nM
2 Kd = 0.13 nM
3 Ki = 0.04 nM
4 Ki = 0.077 nM
5 Ki = 0.08 nM