Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[(3S,9aS)-8-[2-[6-(tetrazol-1-yl)pyridazin-3-yl]acetyl]-3,4,6,7,9,9a-hexahydro-1H-pyrazino[2,1-c][1,4]oxazin-3-yl]-6-fluoro-2-methylbenzonitrile
    Show/Hide
 PubChem ID
CID: 89633466
Canonical SMILES
Cc1c(ccc(F)c1C#N)[C@H]1CN2CCN(C[C@H]2CO1)C(=O)Cc1ccc(nn1)-n1cnnn1
    Show/Hide
Compound Formula C22H22FN9O2
Compound Structure
Protein Name
 Protein Info 
ATP-sensitive inward rectifier potassium channel 1
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Potassium channels
>
Inwardly rectifying potassium channel
Uniprot ID
P48048
Gene Name
KCNJ1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 86 nM
   TI
   LI
   LO
   TS