Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-amino-3,5-dichloro-N-[4-(2-cyanopyrrol-1-yl)-1-(4-methylpiperidin-1-yl)-1-oxobutan-2-yl]benzenesulfonamide
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 PubChem ID
CID: 58509213
Canonical SMILES
CC1CCN(CC1)C(=O)C(CCn1cccc1C#N)NS(=O)(=O)c1cc(Cl)c(N)c(Cl)c1
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Compound Formula C21H25Cl2N5O3S
Compound Structure
Protein Name
 Protein Info 
C-C chemokine receptor type 10
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P46092
Gene Name
CCR10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 15.85 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
IC50 = 1.995 nM
   TI
   LI
   LO
   TS
2
IC50 = 12.59 nM
   TI
   LI
   LO
   TS
3
IC50 = 19.95 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  4
1
IC50 = 3.162 nM
   TI
   LI
   LO
   TS
2
IC50 = 3.4 nM
   TI
   LI
   LO
   TS
3
IC50 = 19.95 nM
   TI
   LI
   LO
   TS
4
IC50 = 158.49 nM
   TI
   LI
   LO
   TS