Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-[2-(6-cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]cyclohexyl]quinoline-4-carboxamide
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 PubChem ID
SID: 14759237
Canonical SMILES
O=C(N[C@H]1CC[C@H](CCN2CCc3cc(ccc3C2)C#N)CC1)c1ccnc2ccccc12
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Compound Formula C28H30N4O
Compound Structure
Protein Name
 Protein Info 
Potassium voltage-gated channel subfamily H member 2
Protein Classification
Ion channel
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Voltage-gated ion channel
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Potassium channels
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Voltage-gated potassium channel
Uniprot ID
Q12809
Gene Name
KCNH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1995.26 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 630.96 nM
   TI
   LI
   LO
   TS
2
IC50 = 676.08 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1995.26 nM
2 Ki = 630.96 nM