Brief Information of the Compound and Protein
Compound Name
Faridak
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PubChem ID
CID: 6918837
SID: 15274143
Canonical SMILES
Cc1[nH]c2ccccc2c1CCNCc1ccc(\C=C\C(=O)NO)cc1
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Compound Formula C21H23N3O2
Compound Structure
Protein Name
Histone deacetylase 2
Protein Classification
Epigenetic regulator
>
Eraser
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Histone deacetylase
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HDAC class I
Uniprot ID
Q92769
Gene Name
HDAC2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000023 BTI-Tn-5B1-4 Trichoplusia ni (Cabbage looper)  1
1
IC50 = 22.83 nM
   TI
   LI
   LO
   TS
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
2
IC50 = 3.28 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3 nM
2 IC50 = 6.8 nM
3 IC50 = 13.2 nM
4 IC50 = 136 nM
5 IC50 < 300 nM
6 Ki = 0.65 nM
7 Ki = 0.7 nM
8 Ki = 1.9 nM
9 Ki = 22 nM