Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)
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 PubChem ID
CID: 2803
SID: 14822899
Canonical SMILES
Clc1cccc(Cl)c1N=C1NCCN1
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Compound Formula C9H9Cl2N3
Compound Structure
Protein Name
 Protein Info 
Alpha-2A adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Adrenergic receptor
Uniprot ID
P08913
Gene Name
ADRA2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
EC50 = 8.318 nM
   TI
   LI
   LO
   TS
2
EC50 = 28 nM
   TI
   LI
   LO
   TS
3
Ki = 3.8 nM
   TI
   LI
   LO
   TS
4
Ki = 8.71 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
EC50 = 30 nM
   TI
   LI
   LO
   TS
2
EC50 = 30.2 nM
   TI
   LI
   LO
   TS
3
Ki = 28 nM
   TI
   LI
   LO
   TS
CL000028 PC-12
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 10 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 3.8 nM
2 Ki = 7.943 nM
3 Ki = 853 nM