Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[1-[3-(dimethylamino)propyl]pyrazol-4-yl]-7-(1H-pyrazol-4-yl)-5H-indeno[1,2-b]indol-10-one
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 PubChem ID
CID: 127052113
Canonical SMILES
CN(C)CCCn1cc(cn1)-c1ccc2C(=O)c3c([nH]c4cc(ccc34)-c3cn[nH]c3)-c2c1
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Compound Formula C26H24N6O
Compound Structure
Protein Name
 Protein Info 
Receptor-type tyrosine-protein kinase FLT3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P36888
Gene Name
FLT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  2
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
2
IC50 = 10 nM
   TI
   LI
   LO
   TS
CL000071 MOLM-13
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
CL000408 MOLM-14
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 11 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4 nM
2 IC50 = 10 nM