Brief Information of the Compound and Protein
Compound Name
(E)-3-(3,4-dimethoxyphenyl)-1-[4-[[2-(3,4-dimethoxyphenyl)quinazolin-4-yl]amino]phenyl]prop-2-en-1-one
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PubChem ID
CID: 127045064
Canonical SMILES
COc1ccc(\C=C\C(=O)c2ccc(Nc3nc(nc4ccccc34)-c3ccc(OC)c(OC)c3)cc2)cc1OC
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Compound Formula C33H29N3O5
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  1
1
IC50 = 190 nM
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