Brief Information of the Compound and Protein
Compound Name
4-chloro-N-(5-cyclopropyl-1,3,4-thiadiazol-2-yl)-1-ethylindazole-6-carboxamide
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PubChem ID
CID: 127047729
Canonical SMILES
CCn1ncc2c(Cl)cc(cc12)C(=O)Nc1nnc(s1)C1CC1
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Compound Formula C15H14ClN5OS
Compound Structure
Protein Name
Prostaglandin E2 receptor EP3 subtype
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
P43115
Gene Name
PTGER3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000064 Chem-1 Rattus norvegicus (Rat)  1
1
Ki = 14.1 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 18.1 nM
   TI
   LI
   LO
   TS