Brief Information of the Compound and Protein
Compound Name
(1R,2R,3R)-2-(4-(5-(difluoromethoxy)pyrimidin-2-yl)phenyl)-N-hydroxy-3-phenylcyclopropanecarboxamide
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PubChem ID
CID: 127028844
Canonical SMILES
O=C(NO)[C@@H]1[C@H](c2ccccc2)[C@H]1c1ccc(-c2ncc(OC(F)F)cn2)cc1
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Compound Formula C21H17F2N3O3
Compound Structure
Protein Name
Histone deacetylase 4
Protein Classification
Epigenetic regulator
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Eraser
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Histone deacetylase
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HDAC class IIa
Uniprot ID
P56524
Gene Name
HDAC4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000081 Jurkat E6.1 Homo sapiens (Human)  1
1
IC50 = 550 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 150 nM