Brief Information of the Compound and Protein
Compound Name
(1R,2R,3R)-2-[4-(5-chloropyrimidin-2-yl)phenyl]-N-hydroxy-3-phenylcyclopropane-1-carboxamide
    Show/Hide
PubChem ID
CID: 60148737
SID: 144076771
Canonical SMILES
ONC(=O)[C@@H]1[C@@H]([C@H]1c1ccc(cc1)-c1ncc(Cl)cn1)c1ccccc1
    Show/Hide
Compound Formula C20H16ClN3O2
Compound Structure
Protein Name
Histone deacetylase 4
Protein Classification
Epigenetic regulator
>
Eraser
>
Histone deacetylase
>
HDAC class IIa
Uniprot ID
P56524
Gene Name
HDAC4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000081 Jurkat E6.1 Homo sapiens (Human)  1
1
IC50 = 430 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 140 nM