Brief Information of the Compound and Protein
Compound Name
(1R,2R,3R)-N-hydroxy-2-[4-(1,3-oxazol-5-yl)phenyl]-3-phenylcyclopropane-1-carboxamide
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PubChem ID
CID: 60148693
SID: 144076726
Canonical SMILES
ONC(=O)[C@@H]1[C@@H]([C@H]1c1ccc(cc1)-c1cnco1)c1ccccc1
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Compound Formula C19H16N2O3
Compound Structure
Protein Name
Histone deacetylase 4
Protein Classification
Epigenetic regulator
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Eraser
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Histone deacetylase
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HDAC class IIa
Uniprot ID
P56524
Gene Name
HDAC4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000081 Jurkat E6.1 Homo sapiens (Human)  3
1
IC50 = 220 nM
   TI
   LI
   LO
   TS
2
IC50 = 230 nM
   TI
   LI
   LO
   TS
3
IC50 > 50000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 20 nM
2 IC50 = 30 nM