Brief Information of the Compound and Protein
Compound Name
3-[(6,7-dimethoxyquinazolin-4-yl)amino]-2,6-difluorophenol
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PubChem ID
CID: 118112040
Canonical SMILES
COc1cc2ncnc(Nc3ccc(F)c(O)c3F)c2cc1OC
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Compound Formula C16H13F2N3O3
Compound Structure
Protein Name
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
IC50 = 4700 nM
   TI
   LI
   LO
   TS
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 230 nM
   TI
   LI
   LO
   TS