Brief Information of the Compound and Protein
Compound Name
 Compound Info 
BMS-907351
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 PubChem ID
CID: 25102847
Canonical SMILES
COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3)c2cc1OC
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Compound Formula C28H24FN3O5
Compound Structure
Protein Name
 Protein Info 
Vascular endothelial growth factor receptor 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35968
Gene Name
KDR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  2
1
GI50 = 3 nM
   TI
   LI
   LO
   TS
2
IC50 = 14 nM
   TI
   LI
   LO
   TS
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.035 nM
2 IC50 = 0.086 nM
3 IC50 = 0.48 nM
4 IC50 = 3 nM
5 IC50 = 3.3 nM
6 IC50 = 4 nM
7 IC50 = 7 nM