Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[6-amino-5-(4-methylsulfonylphenyl)pyridin-3-yl]phenol
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 PubChem ID
CID: 105539853
Canonical SMILES
CS(=O)(=O)c1ccc(cc1)-c1cc(cnc1N)-c1ccc(O)cc1
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Compound Formula C18H16N2O3S
Compound Structure
Protein Name
 Protein Info 
Mitogen-activated protein kinase kinase kinase kinase 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE20 family
>
STE protein kinase MSN subfamily
Uniprot ID
O95819
Gene Name
MAP4K4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000362 GripTite 293 MSR
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2900 nM
   TI
   LI
   LO
   TS
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 19.95 nM
   TI
   LI
   LO
   TS
2
IC50 = 31.62 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 21 nM