Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-(2-(1H-imidazol-2-yl)pyridin-4-yloxy)-N-(3-tert-butylphenyl)-1-methyl-1H-benzo[d]imidazol-2-amine
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 PubChem ID
CID: 60098131
Canonical SMILES
Cn1c(Nc2cccc(C(C)(C)C)c2)nc2cc(Oc3ccnc(-c4ncc[nH]4)c3)ccc21
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Compound Formula C26H26N6O
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000313 SK-MEL-28
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 390 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 90 nM