Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-[2-(3-tert-butylanilino)-1-methylbenzimidazol-5-yl]oxypyridin-2-yl]acetamide
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 PubChem ID
CID: 59790029
Canonical SMILES
CC(=O)Nc1cc(Oc2ccc3n(C)c(Nc4cccc(c4)C(C)(C)C)nc3c2)ccn1
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Compound Formula C25H27N5O2
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000313 SK-MEL-28
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 44 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3 nM