Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-(Benzo[d]thiazol-2-yl)-6-(((1R,2S,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl)amino)-2-(pyrrolidin-1-yl)pyrimidin-4(3H)-one
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 PubChem ID
CID: 136272377
SID: 163597699
Canonical SMILES
O=c1[nH]c(N2CCCC2)nc(N[C@@H]2C[C@H](CO)[C@@H](O)[C@H]2O)c1-c1nc2ccccc2s1
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Compound Formula C21H25N5O4S
Compound Structure
Protein Name
 Protein Info 
Interleukin-1 receptor-associated kinase 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase IRAK family
Uniprot ID
Q9NWZ3
Gene Name
IRAK4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000864 THP1-Xblue
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 78 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 18 nM