Brief Information of the Compound and Protein
Compound Name
5-(benzo[d]thiazol-2-yl)-6-(((3R,6R)-6-methylpiperidin-3-yl)amino)-2-morpholinopyrimidin-4(3H)-one
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PubChem ID
CID: 136932640
Canonical SMILES
C[C@@H]1CC[C@@H](Nc2nc(N3CCOCC3)[nH]c(=O)c2-c2nc3ccccc3s2)CN1
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Compound Formula C21H26N6O2S
Compound Structure
Protein Name
Interleukin-1 receptor-associated kinase 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase IRAK family
Uniprot ID
Q9NWZ3
Gene Name
IRAK4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000864 THP1-Xblue Homo sapiens (Human)  1
1
IC50 = 580 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 93 nM
2 IC50 = 114 nM