Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-[8-[(2R)-2-hydroxy-2-(4-methyl-1-oxo-3H-2-benzofuran-5-yl)ethyl]-2,8-diazaspiro[4.5]decan-2-yl]pyridine-3-carbonitrile
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 PubChem ID
CID: 117852236
Canonical SMILES
Cc1c2COC(=O)c2ccc1[C@@H](O)CN1CCC2(CCN(C2)c2ccc(cn2)C#N)CC1
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Compound Formula C25H28N4O3
Compound Structure
Protein Name
 Protein Info 
ATP-sensitive inward rectifier potassium channel 1
Protein Classification
Ion channel
>
Voltage-gated ion channel
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Potassium channels
>
Inwardly rectifying potassium channel
Uniprot ID
P48048
Gene Name
KCNJ1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS