Brief Information of the Compound and Protein
Compound Name
3-(4-amino-6-methyl-1,3,5-triazin-2-yl)-N-(5-fluoro-6-methoxypyridin-3-yl)-6-(4-(2-methoxyethyl)piperazin-1-yl)imidazo[1,2-a]pyridin-2-amine
    Show/Hide
PubChem ID
CID: 49835172
SID: 103910135
Canonical SMILES
COCCN1CCN(c2ccc3nc(Nc4cnc(OC)c(F)c4)c(-c4nc(C)nc(N)n4)n3c2)CC1
    Show/Hide
Compound Formula C24H29FN10O2
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42336
Gene Name
PIK3CA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000102 U-87MG ATCC Homo sapiens (Human)  1
1
IC50 = 26 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 6.3 nM