Brief Information of the Compound and Protein
Compound Name
3-[[4-[1-[3-(5-chloro-2-methoxyphenyl)-6-[4-(trifluoromethoxy)phenyl]indazol-1-yl]ethyl]benzoyl]amino]propanoic acid
    Show/Hide
PubChem ID
CID: 122189580
Canonical SMILES
COc1ccc(Cl)cc1-c1nn(C(C)c2ccc(cc2)C(=O)NCCC(O)=O)c2cc(ccc12)-c1ccc(OC(F)(F)F)cc1
    Show/Hide
Compound Formula C33H27ClF3N3O5
Compound Structure
Protein Name
Glucagon receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Glucagon-like receptor
>
Glucagon receptor
Uniprot ID
P47871
Gene Name
GCGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
2
IC50 = 36 nM
   TI
   LI
   LO
   TS