Brief Information of the Compound and Protein
Compound Name
(R)-1-Aza-bicyclo[2.2.2]oct-3-yl-[(Z)-methoxyimino]-acetonitrile
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PubChem ID
CID: 9577995
SID: 16130884
Canonical SMILES
CO\N=C(/C#N)[C@H]1CN2CCC1CC2
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Compound Formula C10H15N3O
Compound Structure
Protein Name
Muscarinic acetylcholine receptor M2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Acetylcholine receptor
Uniprot ID
P08172
Gene Name
CHRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 62.1 nM
   TI
   LI
   LO
   TS
2
Ki = 204.17 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 180 nM