Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1S,2R,3R,5R)-3-(hydroxymethyl)-5-[[2-[(2-propan-2-yloxypyridin-4-yl)amino]-5-quinolin-2-ylpyrimidin-4-yl]amino]cyclopentane-1,2-diol
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 PubChem ID
CID: 117885758
Canonical SMILES
CC(C)Oc1cc(Nc2ncc(c(N[C@@H]3C[C@H](CO)[C@@H](O)[C@H]3O)n2)-c2ccc3ccccc3n2)ccn1
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Compound Formula C27H30N6O4
Compound Structure
Protein Name
 Protein Info 
Interleukin-1 receptor-associated kinase 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase IRAK family
Uniprot ID
Q9NWZ3
Gene Name
IRAK4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000864 THP1-Xblue
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 216 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 27 nM