Brief Information of the Compound and Protein
Compound Name
N-[3-hydroxy-4-(4-naphthalen-1-ylpiperazin-1-yl)butyl]quinoline-3-carboxamide
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PubChem ID
CID: 122183764
Canonical SMILES
OC(CCNC(=O)c1cnc2ccccc2c1)CN1CCN(CC1)c1cccc2ccccc12
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Compound Formula C28H30N4O2
Compound Structure
Protein Name
D(3) dopamine receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 13 nM
   TI
   LI
   LO
   TS
2
IC50 = 72 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 3.63 nM
   TI
   LI
   LO
   TS