Brief Information of the Compound and Protein
Compound Name
1-(4-(4-(5-amino-6-(1H-benzo[d][1,2,3]triazol-1-yl)pyrazin-2-yl)-2H-1,2,3-triazol-2-yl)piperidin-1-yl)-2-(dimethylamino)ethanone
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PubChem ID
CID: 122181415
Canonical SMILES
CN(C)CC(=O)N1CCC(n2ncc(-c3cnc(N)c(-n4nnc5ccccc54)n3)n2)CC1
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Compound Formula C21H25N11O
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42336
Gene Name
PIK3CA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000218 BT-474 Homo sapiens (Human)  1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 21 nM