Brief Information of the Compound and Protein
Compound Name
3-[(5-methoxy-1H-indol-3-yl)methyl]-4-methyl-1H-1,2,4-triazol-5-one
    Show/Hide
PubChem ID
CID: 86272986
Canonical SMILES
COc1ccc2[nH]cc(Cc3n[nH]c(=O)n3C)c2c1
    Show/Hide
Compound Formula C13H14N4O2
Compound Structure
Protein Name
Melatonin receptor type 1B
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine-derivative receptor (family A GPCR)
>
Melatonin receptor
Uniprot ID
P49286
Gene Name
MTNR1B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 > 1000 nM
   TI
   LI
   LO
   TS
2
Ki = 560 nM
   TI
   LI
   LO
   TS