Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[2-amino-4-methyl-3-[2-(methylamino)quinazolin-7-yl]oxybenzoyl]-1-methyl-2,5-diphenylpyrazol-3-one
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 PubChem ID
CID: 118730410
Canonical SMILES
CNc1ncc2ccc(Oc3c(C)ccc(C(=O)c4c(-c5ccccc5)n(C)n(-c5ccccc5)c4=O)c3N)cc2n1
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Compound Formula C33H28N6O3
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase B-raf
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P15056
Gene Name
BRAF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000207 MIA PaCa-2
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 190 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 300 nM