Brief Information of the Compound and Protein
Compound Name
4-[2-amino-4-methyl-3-(2-methyl-1,3-benzothiazol-5-yl)benzoyl]-1-methyl-2,5-diphenylpyrazol-3-one
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PubChem ID
CID: 118730417
Canonical SMILES
Cc1nc2cc(ccc2s1)-c1c(C)ccc(C(=O)c2c(-c3ccccc3)n(C)n(-c3ccccc3)c2=O)c1N
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Compound Formula C32H26N4O2S
Compound Structure
Protein Name
Eukaryotic translation initiation factor 2-alpha kinase 3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
>
Other protein kinase PEK family
>
Other protein kinase PEK subfamily
Uniprot ID
Q9NZJ5
Gene Name
EIF2AK3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080 Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CL000043 U2OS Homo sapiens (Human)  1
1
EC50 = 5600 nM
   TI
   LI
   LO
   TS